The star sashayed along the red carpet with partner Brad Pitt in tow, and once inside, the pair were inseparable, stealing kisses and holding hands through-out the ceremony.
Baby news? Angelina Jolie, who arrived on the red carpet at last night's Screen Actors Guild Awards with partner Brad Pitt, did little to quash pregnancy rumours in her flowing Hermès gown
Angelina, who lost out a best actress trophy for A Mighty Heart to Julie Christie, appeared to sip only water, passing on the expensive champagne and wine on offer.
Last week, US reports claimed the 32-year-old is expecting twins, with sources telling Star magazine the couple are "absolutely ecstatic" at the news.
The arrival of twins would bring the Jolie-Pitt brood up to six children, all under the age of seven.
Affectionate: the pair cosied up and stole kisses throughout the night
Family matters: US reports claim Angelina is expecting twins
She already has three adopted children, Maddox, 6, Pax, 4, and Zahara, 3 and a biological daughter, Shiloh, 1.
While Brad's spokesperson refused to comment, the couple have not hidden their desire to have more children.
When Angelina was asked how many she'd like to have, she responded: "Hmm, it fluctuates between seven and 13 or 14. Four is kind of kicking our ass, but we kind of feel like, damn it, we're up for the challenge!"
Brad has said: "We're looking for a soccer team. I want to compete in the next World Cup."
Thrilled: the pair are said to be 'estatic' about the pregnancy news
No alcohol: Angelina was spotted sipping water during the ceremony